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Abadilla, K
Dose-finding study of subcutaneously administered BI 456906 for 16 weeks, compared with placebo and open-label semaglutide in patients with type 2 diabetes mellitus
these are transient and of mild to moderate intensity
Stachulski AV, Knausenberger TB, Shah SN, Hoyles L, McArthur S (2023) A hostgut microbial amino acid co-metabolite, p-cresol glucuronide, promotes bloodbrain barrier integrity in vivo
This insight, which implied that a substance could be harmful at a high dose but beneficial or benign at a low one, directly prefigured the biphasic dose-responses central to hormesis and laid the groundwork for modern toxicology
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